Tilmicosin Solution 10%
This product is a type of macrolide antibiotic to treat the avian respiratory diseases caused by Pasteurella and Mycoplasma, also prevention and treatment of mycoplasma and mycoplasma synovialis.
Advantages:
- Nano-emulsion technology (Oil-In-Water)
- Good absorption and utilization rate, high efficacy, quick and long lasting effect.
- 5-6 hours to reach the peak of blood drug concentration with slow releasing.
- Long half-life, treat once a day.
- High stability, no layering under various temperatures and centrifugation.
Veterinary drug name: Tilmicosin Solution
Main component and chemical name: Tilmicosin, 4A-O-de (2,6-dideoxy -3-C-methyl -L-ribose-pyran hexyl) -20-desoxy-20-(3,5-dimethyl-1-piperidyl)-[20(maleinoid form: trans-form)]tylosin
Character: Light yellow to orange-yellow clear liquid.
Pharmacological action:
Pharmacodynamics:
Timicosin is a semi synthetic macrolide antibiotic specially used for animals. It is strong against mycoplasma with similar antibacterial effect to tylosin. Sensitive gram-positive bacteria including Staphylococcus aureus (including penicillin resistant Staphylococcus aureus), pneumococcus, streptococcus, Bacillus anthracis, erysipelas suis, Listeria, Clostridium putrescence, Clostridium anthracis, etc. Sensitive gram-negative bacteria including haemophilus, meningococcus, pasteurella, etc. The activity against Actinobacillus pleuropneumoniae, Pasteurella and Mycoplasma of livestock and poultry was stronger than tylosin. 95% of Pasteurella haemolytica strains are sensitive to this product.
Pharmacokinetics:
Be absorbed quickly by oral administration, has strong tissue penetration and large distribution volume (>2L/kg). The concentration in lung and milk are high, the half life can reach 1-2 days, effective blood concentration can maintain a long time.
Drug interaction:
1. Can increase the dead of swine if be used together with Adrenalin.
2. It is not suitable to used with other Macrolides, Lincosamides and Chlormycetin because of the similar mechanism of action.
3.There will be antagonism if be used with β-lactam.
4. It has coordinate repression to Rhodococcus equi if used together with penicillin or rifampicin.
Indication: Antibiotics. It is used to cure respiratory disease caused by Mycoplasma and other bacteria, and Pasteurella infection. It can relieve dyspnea, cough and swinging nose etc. rapidly.
Usage and dosage: Oral administration in drinking water, for poultry, Oral administration in drinking water, for the product, 1000ml of it mix with 2000Lof drinking water, once a day, during 3 days.
Adverse reaction: there's no stipulation in standard.
Withdrawal period: 12 days for poultry.
Specification: 10%.
Package: 1L/bottle.
Storage: Sealed, away from light, in dry and cool place.
Expiry: 2 years.
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